Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
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Indonesia orthopedic insole OEM manufacturer

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Eco-friendly pillow OEM manufacturer Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene sheet OEM supplier Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.One-stop OEM/ODM solution provider Vietnam

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Customized sports insole ODM Thailand

Researchers at the Alfred Wegener Institute have found that jellyfish could benefit from climate change, potentially expanding their habitats due to warmer temperatures and other environmental changes. This shift could lead to an increase in jellyfish populations at the expense of fish-dominated ecosystems, particularly in the Arctic Ocean, signaling a significant transformation of marine food webs and impacting fish stocks crucial for commercial fishing. New AWI research reveals that jellyfish in the Arctic Ocean are benefiting from climate change and expanding further north. Climate change is exerting immense pressure on many marine organisms. However, jellyfish across the world’s oceans may find an advantage in increasing water temperatures, particularly in the Arctic Ocean. Researchers at the Alfred Wegener Institute have demonstrated this through computer simulations, exposing eight common Arctic jellyfish species to scenarios of rising temperatures, diminishing sea ice, and other shifting environmental conditions. The result: by the second half of this century, all but one of the species in question could substantially expand their habitat poleward. The ‘lion’s mane jellyfish’ could even triple the size of its habitat – with potentially dramatic consequences for the marine food web and Arctic fish populations. The study was just released in the journal Limnology and Oceanography. In the future, jellyfish and other gelatinous zooplankton could be some of the few organism groups to benefit from climate change. As numerous studies have confirmed, the transparent cnidarians, ctenophores, and pelagic tunicates thrive on rising water temperatures, but also on nutrient contamination and overfishing. When combined, these factors could produce a major shift in the ocean – from a productive, fish-dominated food web to a far less productive ocean full of jellyfish. As such, many researchers are already warning of an impending ‘ocean jellification’, i.e., a worldwide rise in jellyfish populations. The Role of Jellyfish in the Marine Ecosystem “Jellyfish play an important part in the marine food web,” explains Dmitrii Pantiukhin, a postdoctoral researcher in ARJEL (Arctic Jellies), a junior research group specializing in Arctic jellyfish at the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI). “Now that climate change is putting more stress on marine organisms, it can often give the gelatinous zooplankton a leg up on their competitors for food, like fish. This in turn affects the entire food web and ultimately the fish themselves: many types of jellyfish feed on fish larvae and eggs, which can slow or prevent the recovery of fish populations already under pressure, which are often also heavily fished by humans. As such, anyone interested in how fish, an important food source for us, will develop in the future, needs to keep an eye on the jellyfish.” Despite their importance for all marine organisms, the transparent gelatinous organisms are often forgotten or neglected in ecological studies and model-based simulations. The study just released by Dmitrii Pantiukhin and his team closes an important gap in our knowledge, while also concentrating on a hotspot for climate change. “Of all the oceans, the Arctic Ocean is warming the fastest,” says the study’s first author. “In addition, roughly 10 percent of global fishing yields come from the Arctic. As such, the High North is the ideal site for our research.” The jellyfish Cynaea capillata. Credit: Alfred Wegener Institute / Joan J. Soto-Angel A great deal is already known about the physiology of jellyfish, including the optimal temperature range for them to thrive. In the course of the study, the AWI team combined three-dimensional species distribution models with the oceanographic components of the Max Planck Institute Earth System Model (MPI-ESM1.2). “Simulations of species distribution in the ocean are often two-dimensional, a bit like a map,” says Dr Charlotte Havermans, head of the ARJEL junior research group at the AWI. “But the distribution of jellyfish communities in particular is highly dependent on the specific water depth. Consequently, we made our species models three-dimensional. Once we coupled them with the MPI’s Earth system model, we were able to calculate how the distribution of eight major jellyfish species could change from the reference period, 1950 to 2014, to the second half of this century, 2050 to 2099. For future years, we applied the climate scenario ‘ssp370’, that is, a development path where greenhouse-gas emissions remain moderate to high.” Projected Changes in Jellyfish Habitats The results speak for themselves: seven of the eight species – including comb jellies (Beroe sp. / + 110%) and pelagic tunicates (Oikopleura vanhoeffeni / + 102%) – could expand their habitat poleward, in some cases massively, by the period 2050 to 2099, and also stand to gain from the progressive loss of sea ice. The hair jelly Cyanea capillata, colloquially known as the ‘lion’s mane jellyfish’, could especially expand northward, nearly tripling the size of its habitat (+ 180%). Only one of the species investigated (Sminthea arctica) would experience a minor decrease in habitat (- 15%), since it would have to retreat to greater depths to find its optimal temperature range. “These results clearly show how dramatically climate change could affect the ecosystems of the Arctic Ocean,” says AWI expert Dmitrii Pantiukhin. “The projected expansion of the jellyfish habitats could have tremendous, cascading impacts on the entire food web.” One question that remains open is how fish stocks in the Arctic would be affected by a jellyfish expansion. “There are many indications that key Arctic fish species like the polar cod, whose larvae and eggs are frequently eaten by jellyfish, will feel the pressure even more,” says ARJEL Group Leader Charlotte Havermans. “Therefore, our study offers an important basis for further research in this field. And management plans in the fishing sector urgently need to bear in mind this dynamic development in order to avoid the collapse of commercially exploited stocks but manage them sustainably.” Reference: “Pan-Arctic distribution modeling reveals climate-change-driven poleward shifts of major gelatinous zooplankton species” by Dmitrii Pantiukhin, Gerlien Verhaegen and Charlotte Havermans, 15 May 2024, Limnology and Oceanography. DOI: 10.1002/lno.12568

A recent MIT study on mouse behavior in reward-based tasks showed that mice, while capable of learning the best strategy, often deviate from it, suggesting a complex decision-making process. This finding, using a new analysis tool called blockHMM, has potential implications for neurological research, particularly in understanding conditions like schizophrenia and autism. In a simple game that humans typically ace, mice learn the winning strategy, too, but refuse to commit to it, new research shows. Neuroscience discoveries ranging from the nature of memory to treatments for disease have depended on reading the minds of mice, so researchers need to truly understand what the rodents’ behavior is telling them during experiments. In a new study that examines learning from reward, MIT researchers deciphered some initially mystifying mouse behavior, yielding new ideas about how mice think and a mathematical tool to aid future research. Understanding Mice in Learning Experiments The task the mice were supposed to master is simple: Turn a wheel left or right to get a reward and then recognize when the reward direction switches. When neurotypical people play such “reversal learning” games they quickly infer the optimal approach: stick with the direction that works until it doesn’t and then switch right away. Notably, people with schizophrenia struggle with the task. In the new open-access study in PLOS Computational Biology, mice surprised scientists by showing that while they were capable of learning the “win-stay, lose-shift” strategy, they nonetheless refused to fully adopt it. “It is not that mice cannot form an inference-based model of this environment — they can,” says corresponding author Mriganka Sur, the Newton Professor in The Picower Institute for Learning and Memory and MIT’s Department of Brain and Cognitive Sciences (BCS). “The surprising thing is that they don’t persist with it. Even in a single block of the game where you know the reward is 100 percent on one side, every so often they will try the other side.” Exploring Mice’s Decision-Making Strategies While the mouse motif of departing from the optimal strategy could be due to a failure to hold it in memory, says lead author and Sur Lab graduate student Nhat Le, another possibility is that mice don’t commit to the “win-stay, lose-shift” approach because they don’t trust that their circumstances will remain stable or predictable. Instead, they might deviate from the optimal regime to test whether the rules have changed. Natural settings, after all, are rarely stable or predictable. “I’d like to think mice are smarter than we give them credit for,” Le says. But regardless of which reason may cause the mice to mix strategies, adds co-senior author Mehrdad Jazayeri, associate professor in BCS and the McGovern Institute for Brain Research, it is important for researchers to recognize that they do and to be able to tell when and how they are choosing one strategy or another. Analyzing Mice Behavior With New Methods “This study highlights the fact that, unlike the accepted wisdom, mice doing lab tasks do not necessarily adopt a stationary strategy, and it offers a computationally rigorous approach to detect and quantify such non-stationarities,” he says. “This ability is important because when researchers record the neural activity, their interpretation of the underlying algorithms and mechanisms may be invalid when they do not take the animals’ shifting strategies into account.” The research team, which also includes co-author Murat Yildirim, a former Sur lab postdoc who is now an assistant professor at the Cleveland Clinic Lerner Research Institute, initially expected that the mice might adopt one strategy or the other. They simulated the results they’d expect to see if the mice either adopted the optimal strategy of inferring a rule about the task, or more randomly surveying whether left or right turns were being rewarded. Mouse behavior on the task, even after days, varied widely, but it never resembled the results simulated by just one strategy. To differing, individual extents, mouse performance on the task reflected variance along three parameters: how quickly they switched directions after the rule switched, how long it took them to transition to the new direction, and how loyal they remained to the new direction. Across 21 mice, the raw data represented a surprising diversity of outcomes on a task that neurotypical humans uniformly optimize. But the mice clearly weren’t helpless. Their average performance significantly improved over time, even though it plateaued below the optimal level. In the task, the rewarded side switched every 15-25 turns. The team realized the mice were using more than one strategy in each such “block” of the game, rather than just inferring the simple rule and optimizing based on that inference. To disentangle when the mice were employing that strategy or another, the team harnessed an analytical framework called a Hidden Markov Model (HMM), which can computationally tease out when one unseen state is producing a result versus another unseen state. Le likens it to what a judge on a cooking show might do: inferring which chef contestant made which version of a dish based on patterns in each plate of food before them. Before the team could use an HMM to decipher their mouse performance results, however, they had to adapt it. A typical HMM might apply to individual mouse choices, but here the team modified it to explain choice transitions over the course of whole blocks. They dubbed their modified model the blockHMM. Computational simulations of task performance using the blockHMM showed that the algorithm is able to infer the true hidden states of an artificial agent. The authors then used this technique to show the mice were persistently blending multiple strategies, achieving varied levels of performance. “We verified that each animal executes a mixture of behavior from multiple regimes instead of a behavior in a single domain,” Le and his co-authors wrote. “Indeed 17/21 mice used a combination of low, medium, and high-performance behavior modes.” Further analysis revealed that the strategies afoot were indeed the “correct” rule inference strategy and a more exploratory strategy consistent with randomly testing options to get turn-by-turn feedback. Future Research Directions Now that the researchers have decoded the peculiar approach mice take to reversal learning, they are planning to look more deeply into the brain to understand which brain regions and circuits are involved. By watching brain cell activity during the task, they hope to discern what underlies the decisions the mice make to switch strategies. By examining reversal learning circuits in detail, Sur says, it’s possible the team will gain insights that could help explain why people with schizophrenia show diminished performance on reversal learning tasks. Sur added that some people with autism spectrum disorders also persist with newly unrewarded behaviors longer than neurotypical people, so his lab will also have that phenomenon in mind as they investigate. Yildirim, too, is interested in examining potential clinical connections. “This reversal learning paradigm fascinates me since I want to use it in my lab with various preclinical models of neurological disorders,” he says. “The next step for us is to determine the brain mechanisms underlying these differences in behavioral strategies and whether we can manipulate these strategies.” Reference: “Mixtures of strategies underlie rodent behavior during reversal learning” by Nhat Minh Le, Murat Yildirim, Yizhi Wang, Hiroki Sugihara, Mehrdad Jazayeri and Mriganka Sur, 14 September 2023, PLOS Computational Biology. DOI: 10.1371/journal.pcbi.1011430 Funding for the study came from The National Institutes of Health, the Army Research Office, a Paul and Lilah Newton Brain Science Research Award, the Massachusetts Life Sciences Initiative, The Picower Institute for Learning and Memory, and The JPB Foundation.

The somatosensory cortex devotes brain space to detecting touch for each part of the body. The thickness of the cortical region varies among women, associated with its use. The exact location of the brain area representing genital touch varies among women. The new research in JNeurosci also found the region was thicker the more frequently the participants engaged in sexual intercourse. The somatosensory cortex devotes brain space to detecting touch for each part of the body. But the exact location of the female genital field in this map had been controversial. Previous studies produced conflicting results because of less precise mapping methods. Interindividual variability of the genital somatosensory cortex in the MNI space. Credit: Knop et al., JNeurosci 2021 Knop et al. used fMRI to map the exact representation of female genitalia by measuring the brain’s response to a membrane vibrating over the clitoral region. The study was designed to take great care to avoid any discomfort the participants could experience when targeting such a sensitive body region. The somatosensory cortex represented the genitals next to the hips, matching the body’s anatomy. However, the precise location varied from woman to woman. The thickness of the genital field varied with the frequency of sexual intercourse, suggesting the region’s structure alters in relation to its use. These results allow for future studies examining the role of the genital field in healthy sexual function, sexual dysfunction, and especially in the long-term consequences of sexual abuse. Based on this precise mapping, future work can now potentially target the genital representation for treatment of clinical conditions. Reference: “Sensory-Tactile Functional Mapping and Use-Associated Structural Variation of the Human Female Genital Representation Field” by Andrea J. J. Knop, Stephanie Spengler, Carsten Bogler, Carina Forster, Michael Brecht, John-Dylan Haynes and Christine Heim, 8 February 2022, Journal of Neuroscience. DOI: 10.1523/JNEUROSCI.1081-21.2021

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